Title : Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors.

Pub. Date : 2021 Apr

PMID : 33513287






1 Functional Relationships(s)
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1 As a proof of concept, we demonstrated the sensitivity of TGCT cell lines to Olaparib, which associated with differential methylation levels of a subset of targets, namely BRCA1 and RAD51C. olaparib BRCA1 DNA repair associated Homo sapiens