Title : Interfering with lysophosphatidic acid receptor edg2/lpa1 signalling slows down disease progression in SOD1-G93A transgenic mice.

Pub. Date : 2021 Dec

PMID : 33508894






2 Functional Relationships(s)
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Protein Name
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1 Here, we hypothesized that the lipokine lysophosphatidic acid (lpa) regulates MN excitability via the G-protein-coupled receptor lpa1 . lysophosphatidic acid lysophosphatidic acid receptor 1 Mus musculus
2 Conversely, exogenous lpa increased MN excitability by modulating task1 "leak" potassium channels downstream of lpa1 . lysophosphatidic acid lysophosphatidic acid receptor 1 Mus musculus