Title : Prognostic significance of bone marrow FDG uptake in patients with gynecological cancer.

Pub. Date : 2021 Jan 26

PMID : 33500424






2 Functional Relationships(s)
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1 In vitro and in vivo experiments revealed that tumor-derived granulocyte colony-stimulating factor (G-CSF) was involved in the underlying causative mechanism of increased BM FDG-uptake, and that immune suppression mediated by G-CSF-induced myeloid-derived suppressor cells (MDSCs) is responsible for the poor prognosis of this type of cancer. Fluorodeoxyglucose F18 colony stimulating factor 3 Homo sapiens
2 In vitro and in vivo experiments revealed that tumor-derived granulocyte colony-stimulating factor (G-CSF) was involved in the underlying causative mechanism of increased BM FDG-uptake, and that immune suppression mediated by G-CSF-induced myeloid-derived suppressor cells (MDSCs) is responsible for the poor prognosis of this type of cancer. Fluorodeoxyglucose F18 colony stimulating factor 3 Homo sapiens