Pub. Date : 2021 Mar 1
PMID : 33493605
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The solubility of progesterone at 400 mM sulfobutyl-ether-beta-cyclodextrin (SBE-beta-CD) concentration was ~7000-fold greater than its intrinsic solubility, aided by the formation of SBE-beta-CD-progesterone complex. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |
| 2 | The solubility of progesterone at 400 mM sulfobutyl-ether-beta-cyclodextrin (SBE-beta-CD) concentration was ~7000-fold greater than its intrinsic solubility, aided by the formation of SBE-beta-CD-progesterone complex. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |
| 3 | FTIR and NMR studies of the complex confirm the interaction between functional groups of SBE-beta-CD and progesterone to form an inclusion complex. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |
| 4 | Molecular modeling studies demonstrated progesterone binding poses with four probable SBE-beta-CD isomers and these results matched with NMR and FTIR data. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |
| 5 | The progesterone oral formulations were optimized by increasing the levels of SBE-beta-CD in the formulation to prevent the displacement of progesterone from the complex by gastrointestinal contents. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |
| 6 | The progesterone oral formulations were optimized by increasing the levels of SBE-beta-CD in the formulation to prevent the displacement of progesterone from the complex by gastrointestinal contents. | Progesterone | ACD, shelterin complex subunit and telomerase recruitment factor | Rattus norvegicus |