Title : Injectable Polymeric Delivery System for Spatiotemporal and Sequential Release of Therapeutic Proteins To Promote Therapeutic Angiogenesis and Reduce Inflammation.

Pub. Date : 2020 Feb 10

PMID : 33464833






1 Functional Relationships(s)
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1 The sulfonate groups on the thermal gel electrostatically bind to VEGF and IL-10, and their specific binding affinities control their release rates, while PDGF-loaded micelles are embedded in the gel to provide the sequential release of the growth factors. Alkanesulfonates vascular endothelial growth factor A Mus musculus