Title : Metabolic engineering of HEK293 cells to improve transient transfection and cell budding of HIV-1 virus-like particles.

Pub. Date : 2021 Apr

PMID : 33463716






1 Functional Relationships(s)
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1 Overexpression of glycosphingolipid precursor enzyme UGCG improved transfection efficiency by 17% and knocking-down the Gag-binding protein CNP improved 2.5-fold VLP specific productivity. Glycosaminoglycans VHL like Homo sapiens