Title : DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress.

Pub. Date : 2021 Mar

PMID : 33462377






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1 DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress. 3-n-butylphthalide thymoma viral proto-oncogene 1 Mus musculus
2 Moreover, we revealed that DL-NBP administration suppressed oxidative stress by upregulating Nrf2/HO-1 signaling, and increased brain-derived neurotrophic factor (BDNF) expression by activating PI3K/Akt/CREB signaling in the hippocampus. 3-n-butylphthalide thymoma viral proto-oncogene 1 Mus musculus