Title : Deoxidized gulose moiety attenuates the pulmonary toxicity of 6'-deoxy-bleomycin Z without effect on its antitumor activity.

Pub. Date : 2021 Apr

PMID : 33450497






1 Functional Relationships(s)
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1 Further mechanistic studies revealed that the alleviation of pulmonary toxicity in 6"-DO-BLM Z by a slight change in the sugar moiety could attribute to the decrease of ROS production and thereby reduce the subsequent caspase-1 activity and resulting inflammatory response. ros caspase 1 Homo sapiens