Title : HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia.

Pub. Date : 2021 Jan 11

PMID : 33440739






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 17-AAG inhibited HSP90alpha and presented obvious reversal effects of Sorafenib resistance in vivo and in vitro. Sorafenib N-methylpurine DNA glycosylase Homo sapiens
2 All the results emphasized that HSP90alpha plays a critical role in Sorafenib resistance under hypoxia and 17-AAG combined with Sorafenib is a promising therapy for hepatocellular carcinoma. Sorafenib N-methylpurine DNA glycosylase Homo sapiens