Title : Stabilizing the closed SARS-CoV-2 spike trimer.

Pub. Date : 2021 Jan 11

PMID : 33431842






1 Functional Relationships(s)
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1 To support ongoing vaccine development efforts, we report the structure-based design of soluble S trimers with increased yields and stabilities, based on introduction of single point mutations and disulfide-bridges. Disulfides surface glycoprotein Severe acute respiratory syndrome coronavirus 2