Title : Safety, Pharmacokinetic, and Pharmacodynamic Evaluation of a 2'-(2-Methoxyethyl)-D-ribose Antisense Oligonucleotide-Triantenarry N-Acetyl-galactosamine Conjugate that Targets the Human Transmembrane Protease Serine 6.

Pub. Date : 2021 Apr

PMID : 33431610






4 Functional Relationships(s)
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1 Safety, Pharmacokinetic and Pharmacodynamic Evaluation of a 2"-MOE Antisense Oligonucleotide-GalNAc3 Conjugate that Targets the Human Transmembrane Protease Serine 6 (TMPRSS6). galnac3 transmembrane serine protease 6 Homo sapiens
2 Safety, Pharmacokinetic and Pharmacodynamic Evaluation of a 2"-MOE Antisense Oligonucleotide-GalNAc3 Conjugate that Targets the Human Transmembrane Protease Serine 6 (TMPRSS6). galnac3 transmembrane serine protease 6 Homo sapiens
3 ISIS 702843 is a GalNAc3-conjugated 2"-MOE ASO specific for human transmembrane protease, serine 6 (TMPRSS6), and is currently in clinical trials for the treatment of beta-thalassemia. galnac3 transmembrane serine protease 6 Homo sapiens
4 ISIS 702843 is a GalNAc3-conjugated 2"-MOE ASO specific for human transmembrane protease, serine 6 (TMPRSS6), and is currently in clinical trials for the treatment of beta-thalassemia. galnac3 transmembrane serine protease 6 Homo sapiens