Pub. Date : 2021 Jan-Jun
PMID : 33428943
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Androgen receptor splicing variant 7(ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint. | Docetaxel | androgen receptor | Homo sapiens |
| 2 | Recently, aberrant androgen receptor (AR) signaling, including expression of the constitutively active ARV7, was reported to contribute to DTX resistance. | Docetaxel | androgen receptor | Homo sapiens |
| 3 | Recently, aberrant androgen receptor (AR) signaling, including expression of the constitutively active ARV7, was reported to contribute to DTX resistance. | Docetaxel | androgen receptor | Homo sapiens |
| 4 | In sum, our work identified a novel role of ARV7 in promoting DTX resistance and offering a potential path to combat DTX resistance related to abnormal activation of the AR signaling and mitotic dysregulation. | Docetaxel | androgen receptor | Homo sapiens |
| 5 | In sum, our work identified a novel role of ARV7 in promoting DTX resistance and offering a potential path to combat DTX resistance related to abnormal activation of the AR signaling and mitotic dysregulation. | Docetaxel | androgen receptor | Homo sapiens |