Title : Erb‑B2 Receptor Tyrosine Kinase 2 is negatively regulated by the p53‑responsive microRNA‑3184‑5p in cervical cancer cells.

Pub. Date : 2021 Jan

PMID : 33416166






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 The p53 activator Mithramycin A stimulated p53 and miR-3184-5p expression, thereby lowering the levels of ERBB2 and attenuating proliferation, migration and sphere-formation of cervical cancer cells. mithramycin A tumor protein p53 Homo sapiens
2 The p53 activator Mithramycin A stimulated p53 and miR-3184-5p expression, thereby lowering the levels of ERBB2 and attenuating proliferation, migration and sphere-formation of cervical cancer cells. mithramycin A tumor protein p53 Homo sapiens
3 Treatment of cervical cancer cells with the p53 activator Mithramycin A restored the levels of the endogenous ERBB2 inhibitor miR-3184-5p and may represent a novel treatment strategy for cervical cancer. mithramycin A tumor protein p53 Homo sapiens