Pub. Date : 2020
PMID : 33414782
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Overexpression of Gm28309 or inhibition of miR-3068-5p repressed p65 phosphorylation and reduced NLRP3 inflammasome and IL-1beta and IL-18 secretion. | gm28309 | NLR family pyrin domain containing 3 | Homo sapiens |
2 | Conclusions: Our study demonstrates, for the first time, that LncRNAs are involved in regulating immune responses during Brucella infection, and Gm28309, an lncRNA, plays a crucial role in activating NF-kappaB/NLRP3 inflammasome signaling pathway. | gm28309 | NLR family pyrin domain containing 3 | Homo sapiens |