Title : Reducing PD-L1 expression with a self-assembled nanodrug: an alternative to PD-L1 antibody for enhanced chemo-immunotherapy.

Pub. Date : 2021

PMID : 33408792






1 Functional Relationships(s)
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1 Results: Different from ICIs that conformationally block PD-L1 on cancer cell membrane, MS NPs directly reduced the PD-L1 level via metformin to achieve immunotherapy. Metformin CD274 molecule Sus scrofa