Title : Optimum patient selection for irinotecan-containing regimens in metastatic colorectal cancer: Literature review and lessons from clinical practice.

Pub. Date : 2021 Jan-Mar

PMID : 33402591






1 Functional Relationships(s)
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1 Uridine diphosphate glucuronosyltransferase (UGT) gene polymorphisms such as UGT1A1*28/*6, age, performance status, serum lactate dehydrogenase levels, and bilirubin levels could be important considerations for predicting outcomes and tolerability with irinotecan-based regimens. Irinotecan UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens