Title : Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes.

Pub. Date : 2021 Feb 1

PMID : 33399853






2 Functional Relationships(s)
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1 Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes. Calcium transient receptor potential cation channel subfamily V member 4 Homo sapiens
2 Using genetic and reverse genetic approaches combined with biochemical and imaging techniques, we now show that the calcium channel TRPV4 colocalizes with beta1-integrins at the invadosome periphery and regulates its activation and the coupling of acto-adhesive and degradative functions. Calcium transient receptor potential cation channel subfamily V member 4 Homo sapiens