Pub. Date : 2020 Dec 30
PMID : 33396644
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In response to LPS stimulation, the gene expression levels of IL-6 and IL-8 in hGFs increased due to AZM in a concentration-dependent manner, and phosphorylation of nuclear factor kappa B (NF-kappaB) was also promoted. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
2 | Thus, AZM may increase the expression of IL-6 and IL-8 under LPS stimulation to modify the inflammatory response and increase the expression of MMP-1 to promote connective tissue remodeling. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |