Pub. Date : 2021 Feb 24
PMID : 33380469
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Allelic variation in CHRNA3, the gene encoding the alpha3 nicotinic acetylcholine receptor (nAChR) subunit, increases vulnerability to tobacco dependence and smoking-related diseases, but little is known about the role for alpha3-containing (alpha3*) nAChRs in regulating the addiction-related behavioral or physiological actions of nicotine. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 2 | alpha-Conotoxin AuIB, a potent antagonist of the alpha3beta4 nAChR subtype, reduced the stimulatory effects of nicotine on habenular neurons, and its infusion into the IPn increased nicotine intake in rats. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |