Title : Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2.

Pub. Date : 2021 Jan 14

PMID : 33370104






1 Functional Relationships(s)
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1 When the diversity search was extended to nicotinamides, a single fluorine atom addition was found to significantly enhance the permeability, which directly led to the discovery of 7 (BMS-986202) as a clinical Tyk2 inhibitor that binds to Tyk2 JH2. Niacinamide immunoglobulin heavy variable 1-53 Mus musculus