Title : CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.

Pub. Date : 2021 Jan-Jun

PMID : 33361160






1 Functional Relationships(s)
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1 The initial activation step in the gating of ubiquitously expressed Orai1 calcium (Ca2+) ion channels represents the activation of the Ca2+-sensor protein STIM1 upon Ca2+ store-depletion of the endoplasmic reticulum. Calcium stromal interaction molecule 1 Homo sapiens