Title : Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.

Pub. Date : 2021 Feb 8

PMID : 33357454






3 Functional Relationships(s)
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1 Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Arsenic Trioxide tumor protein p53 Homo sapiens
2 Here we report the identification of small molecules, including arsenic trioxide (ATO), an established agent in treating acute promyelocytic leukemia, as cysteine-reactive compounds that rescue structural p53 mutations. Arsenic Trioxide tumor protein p53 Homo sapiens
3 Here we report the identification of small molecules, including arsenic trioxide (ATO), an established agent in treating acute promyelocytic leukemia, as cysteine-reactive compounds that rescue structural p53 mutations. Arsenic Trioxide tumor protein p53 Homo sapiens