Title : A mini-review on ion fluxes that regulate NLRP3 inflammasome activation.

Pub. Date : 2021 Feb 4

PMID : 33355638






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1 In this mini-review, we present a brief summary of the current knowledge about how different ionic flows (including K+, sodium ion, Ca2+, magnesium ion, manganese ion, zinc ion, iron ion, and Cl-) are involved in regulating the NLRP3 inflammasome activation in macrophages. Magnesium NLR family pyrin domain containing 3 Homo sapiens