Pub. Date : 2021 Feb 15
PMID : 33347954
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: ERalpha transfection increased Gli reporter activity in 293FT cells that was further increased by estradiol. | Estradiol | estrogen receptor 1 | Homo sapiens |
| 2 | Acute (2 hr) estradiol increased Gli reporter activity and the formation of intranuclear ERalpha-Gli3 complexes in ER+ BrCa cells but more chronic estradiol (48 hr) reduced ERalpha-Gli complexes commensurate with reduced ERalpha levels. | Estradiol | estrogen receptor 1 | Homo sapiens |
| 3 | Acute (2 hr) estradiol increased Gli reporter activity and the formation of intranuclear ERalpha-Gli3 complexes in ER+ BrCa cells but more chronic estradiol (48 hr) reduced ERalpha-Gli complexes commensurate with reduced ERalpha levels. | Estradiol | estrogen receptor 1 | Homo sapiens |
| 4 | Acute (2 hr) estradiol increased Gli reporter activity and the formation of intranuclear ERalpha-Gli3 complexes in ER+ BrCa cells but more chronic estradiol (48 hr) reduced ERalpha-Gli complexes commensurate with reduced ERalpha levels. | Estradiol | estrogen receptor 1 | Homo sapiens |
| 5 | Fulvestrant or ERalpha knockdown suppressed E2-induction of Gli activity, intranuclear ERalpha-Gli3 complexes and stabilization of Gli3. | Estradiol | estrogen receptor 1 | Homo sapiens |