Pub. Date : 2021 Feb 15
PMID : 33345848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Off-label use of chloroquine, hydroxychloroquine, azithromycin and lopinavir/ritonavir in COVID-19 risks prolonging the QT interval by targeting the hERG channel. | Hydroxychloroquine | ETS transcription factor ERG | Homo sapiens |
| 2 | Clinically, however, many drugs, including those currently used in COVID-19, such as chloroquine, hydroxychloroquine, azithromycin, and lopinavir/ritonavir, may cause cardiotoxicity by acting on cardiac potassium channels and the hERG channel through their off-target effects. | Hydroxychloroquine | ETS transcription factor ERG | Homo sapiens |