Title : Human plasminogen-derived N-acetyl-Arg-Leu-Tyr-Glu antagonizes VEGFR-2 to prevent blood-retinal barrier breakdown in diabetic mice.

Pub. Date : 2021 Feb

PMID : 33338749






1 Functional Relationships(s)
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1 In addition, Ac-RLYE prevented the disruption of adherens and tight junctions and vascular leakage by inhibiting S-nitrosylation of beta-catenin and tyrosine nitration of p190RhoGAP in the retinal vasculature of diabetic mice. ac-rlye Rho GTPase activating protein 35 Mus musculus