Title : Involvement of N-methylpurine DNA glycosylase in resistance to temozolomide in patient-derived glioma cells.

Pub. Date : 2020 Dec 17

PMID : 33335215






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 With that in mind, we evaluated for the first time the degree of resistance to TMZ treatment in 18 patient-derived glioma cells and its association with MGMT and MPG mRNA levels. Temozolomide N-methylpurine DNA glycosylase Homo sapiens
2 mRNA expression analyses showed that the TMZ-resistant phenotype displayed by cells is associated with an elevated expression of MPG to a greater extent than it is with transcript levels of MGMT. Temozolomide N-methylpurine DNA glycosylase Homo sapiens