Pub. Date : 2021 Nov 11
PMID : 33330868
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that thiol-based drugs, cysteamine and WR-1065 (the active metabolite of amifostine) in particular, decrease binding of SARS-CoV-2 spike protein to its receptor, decrease the entry efficiency of SARS-CoV-2 spike pseudotyped virus, and inhibit SARS-CoV-2 live virus infection. | N-(2-mercaptoethyl)-1,3-diaminopropane | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | We found that thiol-based drugs, cysteamine and WR-1065 (the active metabolite of amifostine) in particular, decrease binding of SARS-CoV-2 spike protein to its receptor, decrease the entry efficiency of SARS-CoV-2 spike pseudotyped virus, and inhibit SARS-CoV-2 live virus infection. | N-(2-mercaptoethyl)-1,3-diaminopropane | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |