Title : [Expression of ubiquitin-specific protease 7 in lung tissue of preterm rats after hyperoxia exposure].

Pub. Date : 2020 Dec

PMID : 33328006






2 Functional Relationships(s)
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1 The preterm rats in the intervention groups were given intraperitoneal injection of the USP7 specific inhibitor P5091 (5 mg/kg) every day. P5091 ubiquitin specific peptidase 7 Rattus norvegicus
2 The USP7 specific inhibitor P5091 may accelerate the degradation of beta-catenin by enhancing its ubiquitination, reduce lung epithelial-mesenchymal transition, and thus exert a certain protective effect against hyperoxic lung injury. P5091 ubiquitin specific peptidase 7 Rattus norvegicus