Pub. Date : 2020 Dec 13
PMID : 33322113
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Amino Acid Changes T55A, A273P and R277C in the Beta-Lactamase CTX-M-14 Render E. coli Resistant to the Antibiotic Nitrofurantoin, a First-Line Treatment of Urinary Tract Infections. | Nitrofurantoin | CTX-M-14 | Escherichia coli |
| 2 | Recombinant expression of CTX-M-14 and the mutated CTX-M-14 in the periplasm of E. coli revealed a significant increase in the Minimum Inhibitory Concentration (MIC) for nitrofurantoin from >=6 mug/mL (CTX-M-14) to >=512 mug/mL (mutated CTX-M-14). | Nitrofurantoin | CTX-M-14 | Escherichia coli |
| 3 | Recombinant expression of CTX-M-14 and the mutated CTX-M-14 in the periplasm of E. coli revealed a significant increase in the Minimum Inhibitory Concentration (MIC) for nitrofurantoin from >=6 mug/mL (CTX-M-14) to >=512 mug/mL (mutated CTX-M-14). | Nitrofurantoin | CTX-M-14 | Escherichia coli |
| 4 | Recombinant expression of CTX-M-14 and the mutated CTX-M-14 in the periplasm of E. coli revealed a significant increase in the Minimum Inhibitory Concentration (MIC) for nitrofurantoin from >=6 mug/mL (CTX-M-14) to >=512 mug/mL (mutated CTX-M-14). | Nitrofurantoin | CTX-M-14 | Escherichia coli |
| 5 | Recombinant expression of CTX-M-14 and the mutated CTX-M-14 in the periplasm of E. coli revealed a significant increase in the Minimum Inhibitory Concentration (MIC) for nitrofurantoin from >=6 mug/mL (CTX-M-14) to >=512 mug/mL (mutated CTX-M-14). | Nitrofurantoin | CTX-M-14 | Escherichia coli |