Title : Effects of drug administration on gonadotropins, sex steroid hormones and binding proteins in humans.

Pub. Date : 1987

PMID : 3331377






2 Functional Relationships(s)
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1 (3) Dihydrotestosterone (DHT), the most active androgen in many target cells, given at therapeutic dosages to adult males, resulted in a decrease in plasma concentrations of luteinizing hormone (LH) and T, without any significant change in the percent of free T, even though the affinity of DHT for SBP is higher than that of T. This suggests that the main effect of DHT is to inhibit gonadotropin secretion at the central level. Dihydrotestosterone selenium binding protein 1 Homo sapiens
2 (3) Dihydrotestosterone (DHT), the most active androgen in many target cells, given at therapeutic dosages to adult males, resulted in a decrease in plasma concentrations of luteinizing hormone (LH) and T, without any significant change in the percent of free T, even though the affinity of DHT for SBP is higher than that of T. This suggests that the main effect of DHT is to inhibit gonadotropin secretion at the central level. Dihydrotestosterone selenium binding protein 1 Homo sapiens