Title : Inhibition of CAL27 Oral Squamous Carcinoma Cell by Targeting Hedgehog Pathway With Vismodegib or Itraconazole.

Pub. Date : 2020

PMID : 33312948






2 Functional Relationships(s)
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1 This study aimed to investigate the effects of vismodegib and itraconazole on the expression of Hedgehog (HH) genes (PTCH1, SMO, and GLI1), cell cycle and cell death in OSCC cells. HhAntag691 patched 1 Homo sapiens
2 Gene expression of PTCH1, SMO, and GLI1 decreased in response to 24 h of treatment with vismodegib or itraconazole. HhAntag691 patched 1 Homo sapiens