Title : Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells.

Pub. Date : 2021 Jan-Jun

PMID : 33310702






4 Functional Relationships(s)
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Protein Name
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1 These observations indicate that specifically manipulating CD16a N-glycan composition in CD16a-expressing effector cells including NK cells may improve treatment efficacy. n-glycan Fc gamma receptor IIIa Homo sapiens
2 These observations indicate that specifically manipulating CD16a N-glycan composition in CD16a-expressing effector cells including NK cells may improve treatment efficacy. n-glycan Fc gamma receptor IIIa Homo sapiens
3 However, it is unclear if modifying the expression of select genes that encode processing enzymes in CD16a-expressing effector cells is sufficient to affect N-glycan composition. n-glycan Fc gamma receptor IIIa Homo sapiens
4 N-glycan processing correlated with the expression of glycan modifying genes and thus explained the substantial differences in CD16a processing by NK cells of different origins. n-glycan Fc gamma receptor IIIa Homo sapiens