Title : Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.

Pub. Date : 2021 Jan 11

PMID : 33300026






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intriguingly, from the evolutionarily conserved unstructured domain that targets NEIL1 to open chromatin, its damage surveillance of highly oxidation-susceptible sites to preserve essential gene function and to limit instability and cancer likely originated ~500 million years ago during the buildup of free atmospheric oxygen. Oxygen nei like DNA glycosylase 1 Homo sapiens