Title : Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance.

Pub. Date : 2021 Apr 1

PMID : 33279621






1 Functional Relationships(s)
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1 Here, we showed that the shedding of the mouse NKG2D ligand Rae-1 can be prevented by two critical acetyltransferases, GCN5 and PCAF, which acetylate the lysine residues of Rae-1 to avoid shedding both in vitro and in vivo. Lysine K(lysine) acetyltransferase 2A Mus musculus