Title : [Molecular Mechanism Underlying Inflammatory Cell Death via Necroptosis in M1 Macrophages].

Pub. Date : 2020

PMID : 33268684






2 Functional Relationships(s)
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1 Furthermore, the inhibition of ROS generation suppressed the activation of MLKL and p38 MAPK in zVAD-fmk-treated M1 macrophages. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone mixed lineage kinase domain like pseudokinase Homo sapiens
2 These results indicate that zVAD-fmk-induced cell death occurs via necroptosis through ROS-mediated activation of MLKL and p38 MAPK in M1 macrophages. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone mixed lineage kinase domain like pseudokinase Homo sapiens