Title : The influence of ABO blood groups on COVID-19 susceptibility and severity: A molecular hypothesis based on carbohydrate-carbohydrate interactions.

Pub. Date : 2020 Nov

PMID : 33254482






1 Functional Relationships(s)
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1 Based on this survey, we hypothesize that the correlation between the ABO blood system and susceptibility to SARS-CoV-2 infection can be presumably explained by the modulation of sialic acid-containing receptors distribution on host cell surface induced by ABO antigens through carbohydrate-carbohydrate interactions, which could maximize or minimize the virus Spike protein binding to the host cell. N-Acetylneuraminic Acid surface glycoprotein Severe acute respiratory syndrome coronavirus 2