Title : Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.

Pub. Date : 2021 Jan

PMID : 33239231






1 Functional Relationships(s)
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Protein Name
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1 First, AAT is a serine protease inhibitor (SERPIN) shown to inhibit TMPRSS-2, the host serine protease that cleaves the spike protein of SARS-CoV-2, a necessary preparatory step for the virus to bind its cell surface receptor ACE2 to gain intracellular entry. Serine surface glycoprotein Severe acute respiratory syndrome coronavirus 2