Pub. Date : 2021 Feb
PMID : 33226571
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results also showed that melatonin increased the activity of PI3K/AKT and DNA-PKcs knockdown in melatonin-treated HUVECs that lead to inactivation of PI3K/AKT signaling under oxidative stress with H2O2. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Our results also showed that melatonin increased the activity of PI3K/AKT and DNA-PKcs knockdown in melatonin-treated HUVECs that lead to inactivation of PI3K/AKT signaling under oxidative stress with H2O2. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Our results also showed that melatonin increased the activity of PI3K/AKT and DNA-PKcs knockdown in melatonin-treated HUVECs that lead to inactivation of PI3K/AKT signaling under oxidative stress with H2O2. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Our results also showed that melatonin increased the activity of PI3K/AKT and DNA-PKcs knockdown in melatonin-treated HUVECs that lead to inactivation of PI3K/AKT signaling under oxidative stress with H2O2. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | Furthermore, blockade of PI3K/AKT signal with LY294002 significantly reduced melatonin-induced apoptosis inhibition in H2O2-treated HUVECs. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |
| 6 | Taken together, our findings identify a miR-101/DNA-PKcs/PI3K/AKT signaling pathway in melatonin-induced endothelial cell apoptosis inhibition under oxidative stress with H2O2. | Melatonin | AKT serine/threonine kinase 1 | Homo sapiens |