Pub. Date : 2021 Jan
PMID : 33223202
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structure-based design of glycyrrhetinic acid derivatives as potent anti-sepsis agents targeting high-mobility group box-1. | Glycyrrhetinic Acid | high mobility group box 1 | Mus musculus |
| 2 | Surface plasmon resonance (SPR) was used to verify the binding of GA analogues with HMGB1. | Glycyrrhetinic Acid | high mobility group box 1 | Mus musculus |
| 3 | Molecular modeling predictions further supported these findings, clearly indicating that inhibiting HMGB1 release, using fused heterocyclic GA derivatives, is a promising strategy for treatment of sepsis. | Glycyrrhetinic Acid | high mobility group box 1 | Mus musculus |