Title : Sirtuin 1 and 2 inhibitors enhance the inhibitory effect of sorafenib in hepatocellular carcinoma cells.

Pub. Date : 2021 Feb 5

PMID : 33220273






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 EX-527 reduced MRP3 and BCRP expression in sorafenib-treated HCC cells. Sorafenib ATP binding cassette subfamily C member 3 Homo sapiens
2 Since ABC transporters contribute to MDR, MRP3 and BCRP could be also influencing in the response of HCC cells to sorafenib. Sorafenib ATP binding cassette subfamily C member 3 Homo sapiens