Title : Klotho attenuates angiotensin II‑induced cardiotoxicity through suppression of necroptosis and oxidative stress.

Pub. Date : 2021 Jan

PMID : 33215215






1 Functional Relationships(s)
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1 The pretreatment of H9c2 cells with necrostatin-1 (Nec-1, an inhibitor of necroptosis) or TAK-242 (a small molecule inhibitor of TLR4) attenuated the upregulation of RIP3 and MLKL caused by Ang II. ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate toll-like receptor 4 Rattus norvegicus