Title : Development of a Larval Zebrafish Model for Acute Organophosphorus Nerve Agent and Pesticide Exposure and Therapeutic Evaluation.

Pub. Date : 2020 Nov 17

PMID : 33213094






2 Functional Relationships(s)
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1 The primary mechanism of organophosphorus toxicity is through inhibition of the enzyme acetylcholinesterase, with current emergency treatment including anticholinergics, benzodiazepines, and oxime reactivators. Oximes acetylcholinesterase Danio rerio
2 Additionally, the organophosphorus-specific response for oxime reactivation of acetylcholinesterase was comparable to what has been previously reported. Oximes acetylcholinesterase Danio rerio