Title : Predicting the Animal Susceptibility and Therapeutic Drugs to SARS-CoV-2 Based on Spike Glycoprotein Combined With ACE2.

Pub. Date : 2020

PMID : 33193684






1 Functional Relationships(s)
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1 All the eight compounds can effectively interfere with the binding of ACE2 and Spike protein, especially Nelfinavir, providing drug candidates for the treatment and prevention of SARS-CoV-2, suggesting further assessment of the anti-SARS-CoV-2 activity of these compounds in cell culture. Nelfinavir surface glycoprotein Severe acute respiratory syndrome coronavirus 2