Title : Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.

Pub. Date : 2021 Feb 1

PMID : 33180328






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 beta-thalassemias result from mutations in beta-globin, causing ineffective erythropoiesis and secondary iron overload due to inappropriately low levels of the iron regulatory hormone hepcidin. Iron hemoglobin beta chain complex Mus musculus
2 beta-thalassemias result from mutations in beta-globin, causing ineffective erythropoiesis and secondary iron overload due to inappropriately low levels of the iron regulatory hormone hepcidin. Iron hemoglobin beta chain complex Mus musculus