Title : Predicting the presence and mechanism of busulfan drug-drug interactions in hematopoietic stem cell transplantation using pharmacokinetic interaction network-based molecular structure similarity and network pharmacology.

Pub. Date : 2021 Apr

PMID : 33179758






1 Functional Relationships(s)
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1 The mechanism of busulfan DDI and DILI was attributed mostly to CYP450s, GSTs, and ABC transporters, and PXR was identified as a potential target. Busulfan hematopoietic prostaglandin D synthase Homo sapiens