Title : Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis.

Pub. Date : 2021 Jan 1

PMID : 33171207






1 Functional Relationships(s)
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1 By using calcium channel blocker Nimodipine, the increase of intracellular Ca2+ was attenuated, and the death rate of neurons, the ROS and opening of mPTP, decreased ATP production, the expressions of cytochrome c, cleaved caspase-9, cleaved caspase-3 and the ratio of Bax/Bcl-2 were alleviated. Calcium BCL2 associated X, apoptosis regulator Homo sapiens