Title : Identification of curcumin as a novel natural inhibitor of rDNA transcription.

Pub. Date : 2020 Dec

PMID : 33171062






1 Functional Relationships(s)
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1 Mechanistically, curcumin inactivates the mechanistic target of rapamycin complex 1 (mTORC1), the upstream regulator of rDNA transcription and autophagy induction, by inhibiting mTOR lysosomal localization. Curcumin CREB regulated transcription coactivator 1 Mus musculus