Pub. Date : 2021 Jan 1
PMID : 33160991
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ambient fine particulate matter aggravates atherosclerosis in apolipoprotein E knockout mice by iron overload via the hepcidin-ferroportin axis. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 2 | SIGNIFICANCE: PM2.5 inhalation could exacerbate the formation and development of atherosclerosis in ApoE-/- mice, the potential mechanisms may be partly associated with iron overload via the hepcidin-FPN axis, as well as iron-triggered systemic inflammation and hyperlipidemia. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 3 | SIGNIFICANCE: PM2.5 inhalation could exacerbate the formation and development of atherosclerosis in ApoE-/- mice, the potential mechanisms may be partly associated with iron overload via the hepcidin-FPN axis, as well as iron-triggered systemic inflammation and hyperlipidemia. | Iron | hepcidin antimicrobial peptide | Mus musculus |