Title : SIRT3 protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway.

Pub. Date : 2021 Jan 1

PMID : 33160987






1 Functional Relationships(s)
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1 However, transfection with adenoviral construct including SIRT3 significantly inhibited HG-induced SA-gal activity, decreased p53 acetylation level at the site Lys 320 (k320), and overexpression of SIRT3 antagonized high glucose-induced angiogenic dysfunction. Lysine tumor protein p53 Homo sapiens